N-(3-氯-2-甲基-苯基)-甲酰胺合成路线 （共 4 条）
反应条件
1: With borane-THF in tetrahydrofuran T=-40 - 20°C; 2: With hydrogenchloride; water in tetrahydrofuran T=20°C; 3: With sodium hydroxide in water; acetonitrile
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BIOLIPOX AB
Patent: WO2008/129288 A2, 2008 ;
Location in patent: Page/Page column 57 ;
WO 2008/129288 A2
反应条件
Bromieren und Verseifen des erhaltenen Produkts;
参考文献
Farbwerke Hoechst
Priv.-Mitt.
反应条件
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane
T=0 - 20°C; 12 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BIOLIPOX AB
Patent: WO2008/129288 A2, 2008 ;
Location in patent: Page/Page column 56 ;
WO 2008/129288 A2
反应条件
in water
24 h; Reflux;
参考文献
Kaboudin, Babak; Khodamorady, Minoo
Synlett, 2010 , # 19 p. 2905 - 2907
