5-溴-6-硝基-1H-吲唑合成路线 （共 3 条）
反应条件
acetic acid; sodium nitrite in water
T=20°C; 72 h;
参考文献
Zhu, Gui-Dong; Gong, Jianchun; Gandhi, Viraj B.; Woods, Keith; Luo, Yan; Liu, Xuesong; Guan, Ran; Klinghofer, Vered; Johnson, Eric F.; Stoll, Vincent S.; Mamo, Mulugeta; Li, Qun; Rosenberg, Saul H.; Giranda, Vincent L.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 6 p. 2441 - 2452
反应条件
sodium hydroxide; sodium hypochlorite in water
T=0°C; 5 h;
参考文献
Zhu, Gui-Dong; Gong, Jianchun; Gandhi, Viraj B.; Woods, Keith; Luo, Yan; Liu, Xuesong; Guan, Ran; Klinghofer, Vered; Johnson, Eric F.; Stoll, Vincent S.; Mamo, Mulugeta; Li, Qun; Rosenberg, Saul H.; Giranda, Vincent L.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 6 p. 2441 - 2452
反应条件
1: 92 percent / triethylamine; 4-(dimethylamino)pyridine / acetonitrile / 15 h / 20 °C
2: 97 percent / hydrogen / nickel / tetrahydrofuran; H2O / 6 h / 20 °C
View Scheme
参考文献
Zhu, Gui-Dong; Gong, Jianchun; Gandhi, Viraj B.; Woods, Keith; Luo, Yan; Liu, Xuesong; Guan, Ran; Klinghofer, Vered; Johnson, Eric F.; Stoll, Vincent S.; Mamo, Mulugeta; Li, Qun; Rosenberg, Saul H.; Giranda, Vincent L.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 6 p. 2441 - 2452
