2-乙酰氨基-5-溴吡啶合成路线 （共 12 条）
参考文献
Sollogoub, Matthieu; Fox, Keith R.; Powers, Vicki E.C.; Brown, Tom
Tetrahedron Letters, 2002 , vol. 43, # 17 p. 3121 - 3123
反应条件
acetic anhydride in acetic acid
参考文献
Lee, Jae-Gul; Leem, Won-Bin; Cho, Jong-Hwan; Choi, Sung-Hak; Lee, Jong-Jin; Park, Sang-Kuk; Lee, Tae-Hoo; Kim, Dong-Goo; Sung, Hyun-Jung
Patent: US2003/166620 A1, 2003 ;
反应条件
[Pd(dippf)Cl2]; triethylamine in acetonitrile T=140°C; 1 h; Microwave irradiation; chemoselective reaction;
参考文献
Fuentes, Jose A.; Clarke, Matthew L.
Synlett, 2008 , # 17 p. 2579 - 2582
反应条件
copper(l) chloride in methanol
参考文献
WO2007/124345 A2, ;
Page/Page column 24-25 ;
反应条件
triethylamine 48 h; Heating / reflux;
参考文献
US2004/102450 A1, ;
Page/Page column 79 ;
反应条件
toluene-4-sulfonic acid; potassium iodide; sodium nitrite in acetonitrile T=20°C;
参考文献
Synthesis, , # 1 p. 81 - 84
反应条件
ozone; sodium sulfite 1.) AcOEt, -60 deg C, 7 min, 2.) AcOEt; Yield given. Multistep reaction;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 40, # 3 p. 666 - 674
反应条件
potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in N,N-dimethyl-formamide T=80°C; 15 h;
参考文献
WO2006/79791 A1, ;
Page/Page column 42 ;
WO 2006/079791 A1
反应条件
sodium tetrahydroborate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; N,N,N',N,-tetramethylethylenediamine in tetrahydrofuran T=25°C; 2 h; Inert atmosphere;
参考文献
Chelucci, Giorgio
Tetrahedron Letters, 2010 , vol. 51, # 12 p. 1562 - 1565
