2-氨基-N-2-萘基-乙酰胺合成路线 （共 4 条）
反应条件
glycyl aminopeptidase from Actinomucor elegans; tris(hydroxymethyl)methylamine hydrochloride T=37°C; pH=7.0; Enzyme kinetics;
参考文献
Ito, Kiyoshi; Ma, Xiaohang; Azmi, Nik; Huang, Hua-Shan; Fujii, Mikio; Yoshimoto, Tadashi
Bioscience, biotechnology, and biochemistry, 2003 , vol. 67, # 1 p. 83 - 88
反应条件
10 Pd/C; hydrogen in ethyl acetate
P=2280.15 Torr;
参考文献
Dosa, Stefan; Stirnberg, Marit; Luelsdorff, Verena; Haeussler, Daniela; Maurer, Eva; Guetschow, Michael
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 21 p. 6489 - 6505,17
反应条件
1: (i) ClCO2iBu, nBu3N, CHCl3, (ii) /BRN= 606264/
2: H2, HCl / Pd-C / ethanol
View Scheme
参考文献
Goldstein,T.P. et al.
Journal of Medicinal and Pharmaceutical Chemistry, 1962 , vol. 5, p. 852 - 857
反应条件
piperidine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid
1.) DMF, 2.) CH2Cl2; Yield given. Multistep reaction;
参考文献
Garigipati, Ravi S.
Tetrahedron Letters, 1997 , vol. 38, # 39 p. 6807 - 6810
