2-乙酰氧基-3-甲氧基苯甲醛合成路线 （共 22 条）
反应条件
1: 99 percent / Br2, potassium bromide / H2O / 24 h / 25 °C 2: 95 percent / aq. NaOH / 4 h / 25 °C 3: 82 percent / aq. NaOH, H2O2 / 4 h / 25 °C 4: K2CO3, cupric oxide / 5.5 h / 110 °C 5: 1.) butyllithium / 1.) hexane, ether, from -20 deg C to -10 deg C, 30 min, 2.) hexane, ether, RT, 30 min View Scheme
参考文献
Simig, Gy.; Schlosser, M.
ACH - Models in Chemistry, 1994 , vol. 131, # 2 p. 217 - 228
反应条件
bromine; potassium bromide in water 1 h;
参考文献
Journal of Organic Chemistry, , vol. 52, # 20 p. 4485 - 4489
反应条件
1: 1.) Br2, KBr, 2.) NaOH / 1.) H2O, 6 h, 2.) H2O, 6 h 2: 96 percent / K2CO3 / dimethylformamide / 5 h / 110 - 120 °C 3: 70 percent / KMnO4 / acetone; H2O / 3 h / 50 - 60 °C View Scheme
参考文献
Nimgirawath, Surachai; Ponghusabun, Ong-ard
Australian Journal of Chemistry, 1994 , vol. 47, # 5 p. 951 - 956
反应条件
1: With 1,8-diazabicyclo[5.4.0]undec-7-ene; sodium iodide in tetrahydrofuran T=-78°C; Horner-Wadsworth-Emmons reaction; 2: With potassium hydroxide in methanol T=20°C; 0.25 h;
参考文献
Takeuchi, Yasuo; Ueda, Norihiro; Uesugi, Koji; Abe, Hitoshi; Nishioka, Hiromi; Harayama, Takashi
Heterocycles, 2003 , vol. 59, # 1 p. 217 - 224
反应条件
1: 81 percent / benzene / 48 h / Heating 2: 74 percent / potassium acetate / 0.17 h / Heating View Scheme
参考文献
Rizzacasa, Mark A.; Sargent, Melvyn V.
Australian Journal of Chemistry, 1987 , vol. 40, # 10 p. 1737 - 1743
反应条件
pyridine
24 h; Ambient temperature;
参考文献
Wriede, Ulrich; Fernandez, Mario; West, Kevin F.; Harcourt, Dale; Moore, Harold W.
Journal of Organic Chemistry, 1987 , vol. 52, # 20 p. 4485 - 4489
反应条件
acetic anhydride; 2-(N,N-dimethylamino)-pyridine in (N,N)-diisopropylethylamine
参考文献
Pettit, George R.; Grealish, Matthew P
Patent: US2003/220304 A1, 2003 ;
反应条件
trimethylsilyl trifluoromethanesulfonate in acetonitrile
T=20°C;
参考文献
Williams, Craig M.; Mander, Lewis N.
Tetrahedron Letters, 2004 , vol. 45, # 4 p. 667 - 669
参考文献
Robinson; Beyer
Archiv der Pharmazie (Weinheim, Germany), 1915 , vol. 253, p. 380
反应条件
sulfuric acid; nitric acid
T=-40°C; 0.0833333 h;
参考文献
Kato, Shiro; Morie, Toshiya
Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 4 p. 1171 - 1178
