N-(5-氯-4-甲基-2-硝基苯基)乙酰胺合成路线 (共 3 条)
反应条件
sulfuric acid; potassium nitrate T=5°C;
参考文献
NOVASAID AB; WANNBERG, Johan; ALTERMAN, Mathias; MALM, Johan; STENBERG, Patric; WESTMAN, Jacob; WALLBERG, Hans
Patent: WO2011/23812 A1, 2011 ;
Location in patent: Page/Page column 164 ;
WO 2011/023812 A1
参考文献
Journal of the Chemical Society, , vol. 119, p. 868
Journal of the Chemical Society, , vol. 121, p. 809
反应条件
methanol; sodium methylate T=20°C; 5 h;
参考文献
BIORELIX PHARMACEUTICALS, INC.; DIXON, Brian, R.; BLOUNT, Kenneth, F.; BERMAN, Judd; COISH, Philip, D.G.; OSTERMAN, David; HARPREET, Kaur; KELLS, Kevin; WICKENS, Phil; WILSON, Jeffrey; WU, Justin
Patent: WO2010/19208 A1, 2010 ;
Location in patent: Page/Page column 167-168 ;