1-(4-氟苯基)环己烷甲腈合成路线 （共 3 条）
反应条件
sodium hydride in N,N-dimethyl-formamide; mineral oil T=20°C; 3 h; Cooling with ice;
参考文献
Watanuki, Susumu; Matsuura, Keisuke; Tomura, Yuichi; Okada, Minoru; Okazaki, Toshio; Ohta, Mitsuaki; Tsukamoto, Shin-Ichi
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 18 p. 5628 - 5638
反应条件
sodium hexamethyldisilazane Inert atmosphereSchlenk technique;
参考文献
Journal of the American Chemical Society, , vol. 135, # 34 p. 12576 - 12579
反应条件
1: diisobutylaluminium hydride / |Inert atmosphere; |Schlenk technique 2: iron tribromide / toluene / 14 h / 130 °C / |Sealed tube; |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Gutierrez-Bonet, Alvaro; Flores-Gaspar, Areli; Martin, Ruben
Journal of the American Chemical Society, 2013 , vol. 135, # 34 p. 12576 - 12579
