1-(1-吡咯烷)环戊烯合成路线 （共 78 条）
反应条件
1: NaI / ethanol / 4 h / Heating
2: 95 percent / t-C5H11ONa / toluene / 80 °C
View Scheme
参考文献
Pal, Sitaram; Mukhopadhyaya, Jayanta K.; Ghatak, Usha Ranjan
Journal of Organic Chemistry, 1994 , vol. 59, # 10 p. 2687 - 2694
反应条件
1: With titanium tetrachloride; zinc in tetrahydrofuran
0.25 h;
2: With sodium hydroxide in tetrahydrofuran; water
参考文献
Wyeth
Patent: US2004/19040 A1, 2004 ;
Location in patent: Page/Page column 9-10 ;
US 20040019040 A1
反应条件
zinc dibromide in chloroform
T=90 - 100°C; 2 h; Yield given;
参考文献
Koyama, Junko; Toyokuni, Izumi; Tagahara, Kiyoshi
Chemical and Pharmaceutical Bulletin, 1998 , vol. 46, # 2 p. 332 - 334
参考文献
Severin,T.; Ipach,I.
Chemische Berichte, 1976 , vol. 109, p. 3541 - 3546
参考文献
Bayer Aktiengesellschaft
Patent: US4185112 A1, 1980 ;
反应条件
1: in acetonitrile
Inert atmosphereReflux;
2: With water in acetonitrile
1 h; Inert atmosphereReflux;
参考文献
Roscini, Claudio; Cubbage, Kara L.; Berry, Malcolm; Orr-Ewing, Andrew J.; Booker-Milburn, Kevin I.
Angewandte Chemie - International Edition, 2009 , vol. 48, # 46 p. 8716 - 8720
反应条件
in chloroform
1.) 25 deg C, 1.5 h, 2.) 45 deg C, 35 h;
参考文献
Boger, Dale L.; Panek, James S.
Journal of Organic Chemistry, 1981 , vol. 46, # 10 p. 2179 - 2182
反应条件
ethylmagnesium bromide; diisopropylamine in diethyl ether
T=0 - 20°C;
参考文献
Kobayashi, Kazuhiro; Kawakita, Masataka; Irisawa, Susumu; Akamatsu, Hideki; Sakashita, Kouji; Morikawa, Osamu; Konishi, Hisatoshi
Tetrahedron, 1998 , vol. 54, # 12 p. 2691 - 2696
