1-(1-吡咯烷)环戊烯合成路线 （共 78 条）
反应条件
1: 48 percent / Triethylamine / CH2Cl2 / 1.) 1 h, -20 deg C, 2.) rt
2: 88 percent / sat. ethanolic NH3 / 96 h / Ambient temperature
3: 38 percent / sodium ethoxide / ethanol / 18 h / Heating
View Scheme
参考文献
Taylor; Fletcher
Journal of Organic Chemistry, 1984 , vol. 49, # 17 p. 3226 - 3227
反应条件
1: H2O / reflux, dioxane, 12 h
2: 88 percent / NaBH4 / tetrahydrofuran
3: 89 percent / CH2Cl2 / 19 h / Heating
View Scheme
参考文献
Clive, Derrick L. J.; Beaulieu, Pierre L.; Set, Lu
Journal of Organic Chemistry, 1984 , vol. 49, p. 1313 - 1314
反应条件
1: H2O / reflux, dioxane, 12 h
2: 88 percent / NaBH4 / tetrahydrofuran
View Scheme
参考文献
Clive, Derrick L. J.; Beaulieu, Pierre L.; Set, Lu
Journal of Organic Chemistry, 1984 , vol. 49, p. 1313 - 1314
反应条件
in ethanol
2 h; Heating;
参考文献
Marcelis, Antonius T. M.; Plas, Henk C. van der
Tetrahedron, 1989 , vol. 45, # 9 p. 2693 - 2702
反应条件
1: 2) H2O / 1) dioxane, 120 deg C, 5 h, 2) dioxane, reflux, 1 h
2: 39.4 percent / Ac2O, azeotropic HBr in H2O / 4 h / 140 °C
View Scheme
参考文献
Rejzek; Wimmer; Saman; Ricankova; Nemec
Helvetica Chimica Acta, 1994 , vol. 77, # 5 p. 1241 - 1255
参考文献
Rao, T. Vedagiriswara; Anandan, Lalitha; Mathur, H. H.; Trivedi, G. K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 9 p. 864 - 867
参考文献
Rao, T. Vedagiriswara; Anandan, Lalitha; Mathur, H. H.; Trivedi, G. K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 9 p. 864 - 867
反应条件
in dichloromethane
T=0°C; 0.08 h;
参考文献
Sparey, Tim J.; Harrison, Timothy
Tetrahedron Letters, 1998 , vol. 39, # 32 p. 5873 - 5874
反应条件
hydrogenchloride; tetramethyl-ammonium fluoride
1) DMF, 70 deg C, 6 h, irradiated 2) r.t., 3 h; Yield given. Multistep reaction;
参考文献
Chen, Qing-Yun; Li, Zhan-Ting
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 6 p. 645 - 648
参考文献
Semisch, Christoph; Margaretha, Paul
Journal of Fluorine Chemistry, 1985 , vol. 30, p. 471 - 475
