环丙基(4-甲基苯基)-甲酮合成路线 (共 21 条)
反应条件
potassium hydroxide in methanol T=8 - 10°C; 0.333333 h;
参考文献
Merrell Pharmaceuticals Inc.
Patent: US6340761 B1, 2002 ;
Location in patent: Page column 25-26 ;
反应条件
1: para-bromotoluene With n-butyllithium in hexane T=0 - 20°C; 4 h; Inert atmosphere; 2: cyclopropanecarbonitrile in hexane T=20°C; 0.166667 h; Inert atmosphere; 3: With toluene-4-sulfonic acid in hexane; water T=20°C; 0.5 h; Inert atmosphere;
参考文献
Huang, Huawen; Ji, Xiaochen; Wu, Wanqing; Jiang, Huanfeng
Chemical Communications, 2013 , vol. 49, # 32 p. 3351 - 3353
反应条件
sodium carbonate in various solvent(s) T=80°C; 216 h; Further byproducts given;
参考文献
Journal of Organic Chemistry, , vol. 48, # 26 p. 5260 - 5268
反应条件
triethylamine in ethanol; water T=25°C; 24 h; Further byproducts given;
参考文献
Journal of Organic Chemistry, , vol. 48, # 26 p. 5260 - 5268
反应条件
sodium carbonate in various solvent(s) T=25°C; 24 h; Further byproducts given;
参考文献
Journal of Organic Chemistry, , vol. 48, # 26 p. 5260 - 5268
反应条件
sodium carbonate in various solvent(s) T=80°C; 9 h; Further byproducts given;
参考文献
Journal of Organic Chemistry, , vol. 48, # 26 p. 5260 - 5268
反应条件
sodium carbonate in various solvent(s) T=80°C; 216 h; Further byproducts given;
参考文献
Journal of Organic Chemistry, , vol. 48, # 26 p. 5260 - 5268
反应条件
T=20°C; Irradiation;
参考文献
Journal of the American Chemical Society, , vol. 118, # 32 p. 7473 - 7477
反应条件
T=20°C; Irradiation;
参考文献
Journal of the American Chemical Society, , vol. 118, # 32 p. 7473 - 7477
反应条件
sodium carbonate T=80°C; 216 h; Further byproducts given;
参考文献
Journal of Organic Chemistry, , vol. 48, # 26 p. 5260 - 5268