(3-乙氧基-4-甲氧基苯基)乙酸合成路线 （共 6 条）
反应条件
1: With caesium carbonate in acetone
T=65°C; 3.5 h;
2: With lithium hydroxide; water in tetrahydrofuran
T=70°C; 2.5 h;
3: With hydrogenchloride in water
参考文献
GENENTECH, INC.; CURIS, INC.
Patent: WO2008/137408 A1, 2008 ;
Location in patent: Page/Page column 33 ;
WO 2008/137408 A1
反应条件
1: copper oxide-chromium oxide; ethanol / Hydrogenation
2: benzene; hexane; HCl / -10 °C
3: aqueous acetone
4: aqueous NaOH
View Scheme
参考文献
Shepard; Noth
Journal of the American Chemical Society, 1950 , vol. 72, p. 4364,4366
参考文献
Shepard; Noth
Journal of the American Chemical Society, 1950 , vol. 72, p. 4364,4366
反应条件
1: aqueous acetone
2: aqueous NaOH
View Scheme
参考文献
Shepard; Noth
Journal of the American Chemical Society, 1950 , vol. 72, p. 4364,4366
反应条件
1: benzene; hexane; HCl / -10 °C
2: aqueous acetone
3: aqueous NaOH
View Scheme
参考文献
Shepard; Noth
Journal of the American Chemical Society, 1950 , vol. 72, p. 4364,4366
反应条件
sodium hydroxide; dihydrogen peroxide
参考文献
Barger et al.
Chemische Berichte, 1933 , vol. 66, p. 450,459
