5-(1-哌啶基甲基)-2-噻吩甲醛合成路线 （共 3 条）
反应条件
caesium carbonate; palladium diacetate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in tetrahydrofuran; water
T=80°C; Suzuki-Miyaura cross-coupling reaction; 24 h;
参考文献
Molander, Gary A.; Gormisky, Paul E.; Sandrock, Deidre L.
Journal of Organic Chemistry, 2008 , vol. 73, # 6 p. 2052 - 2057
反应条件
palladium diacetate; caesium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in tetrahydrofuran; water
T=80°C; Suzuki-Miyaura coupling; 45 h;
参考文献
Raushel, Jessica; Sandrock, Deidre L.; Josyula, Kanth V.; Pakyz, Deborah; Molander, Gary A.
Journal of Organic Chemistry, 2011 , vol. 76, # 8 p. 2762 - 2769
反应条件
1: tetrahydrofuran; tert-butyl alcohol / 2 h / 80 °C / Inert atmosphere
2: palladium diacetate; caesium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl / tetrahydrofuran; water / 45 h / 80 °C
View Scheme
参考文献
Raushel, Jessica; Sandrock, Deidre L.; Josyula, Kanth V.; Pakyz, Deborah; Molander, Gary A.
Journal of Organic Chemistry, 2011 , vol. 76, # 8 p. 2762 - 2769
