1: 2-(benzenesulfonylmethyl)pyridine N-oxide With sulfur; potassium tert-butylate in tetrahydrofuran T=20°C; 12 h; 2: methyl iodide in tetrahydrofuran T=20°C; 1 h;

1.1: 92 percent / MCPBA / CH2Cl2 / 12 h / 0 - 20 °C 2.1: S8; t-BuOK / tetrahydrofuran / 12 h / 20 °C 2.2: 71 percent / tetrahydrofuran / 1 h / 20 °C View Scheme

1.1: 98 percent / tetrapropylammonium bromide; DBU / acetonitrile / 24 h / 80 °C 2.1: 92 percent / MCPBA / CH2Cl2 / 12 h / 0 - 20 °C 3.1: S8; t-BuOK / tetrahydrofuran / 12 h / 20 °C 3.2: 71 percent / tetrahydrofuran / 1 h / 20 °C View Scheme