3-(4-氨基苯基)丙酸乙酯合成路线 （共 9 条）
反应条件
lithium aluminium tetrahydride
参考文献
Oki; Iwamura
Bulletin of the Chemical Society of Japan, 1959 , vol. 32, p. 1135,1136
反应条件
hydrogen; palladium on activated charcoal in ethanol
P=2585.7 Torr; 6 h;
参考文献
Johnson; Silver; Becker; Birsner; Bohnet; Briggs; Busacca; Canniff; Carabateas; Chadwick; D'Ambra; Dundore; Dung; Ezrin; Gorczyca; Habeeb; Horan; Krafte; Pilling; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 14 p. 2551 - 2556
反应条件
palladium monocarbide in tetrahydrofuran
参考文献
Takeda Chemical Industries, Ltd.
Patent: US6235731 B1, 2001 ;
反应条件
hydrogenchloride; hydrogen; palladium-on-activated charcoal in ethanol; water
参考文献
Bristol-Myers Squibb Company
Patent: US5470845 A1, 1995 ;
反应条件
hydrogen in ethyl acetate
T=25°C; P=7600.51 Torr; 53 h; Autoclave; chemoselective reaction;
参考文献
Motoyama, Yukihiro; Taguchi, Masahiro; Desmira, Nelfa; Yoon, Seong-Ho; Mochida, Isao; Nagashima, Hideo
Chemistry - An Asian Journal, 2014 , vol. 9, # 1 p. 71 - 74
参考文献
Flynn, Daniel L.; Petillo, Peter A.
Patent: US2008/248548 A1, 2008 ;
反应条件
Basolite® A100; ammonia; hydrazine hydrate in acetonitrile
T=25°C; 24 h; chemoselective reaction;
参考文献
Dhakshinamoorthy, Amarajothi; Alvaro, Mercedes; Garcia, Hermenegildo
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 14-15 p. 2271 - 2276
反应条件
1: 150 °C
2: benzene; POCl3
3: aqueous HCl
View Scheme
参考文献
Everett et al.
Journal of the Chemical Society, 1953 , p. 2386,2387
反应条件
1: 2.) triethyl phosphite / 1.) methanol, 4 h, reflux; 2.) 8 h, 150 deg C
2: 77 percent / NaOH / ethanol; H2O / 12 h / Heating
View Scheme
参考文献
Picciola; Ravenna; Carenini; Gentili; Riva
Farmaco, Edizione Scientifica, 1981 , vol. 36, # 12 p. 1037 - 1056
