1: 1-trifluoromethyl-4-bromobenzene With magnesium in tetrahydrofuran T=20°C; Inert atmosphere; 2: N-methoxy-N-methylpropionamide in tetrahydrofuran T=-20 - 20°C; Inert atmosphere; 3: With water in tetrahydrofuran
参考文献
Ueno, Satoshi; Shimizu, Ryosuke; Kuwano, Ryoichi
Angewandte Chemie, International Edition, 2009 , vol. 48, p. 4543 - 4545
Angewandte Chemie, 2009 , vol. 121, p. 4613 - 4615
water; oxygen; copper(l) iodide; palladium dichloride in N,N-dimethyl-formamide T=50°C; Wacker oxidation; 24 h; Title compound not separated from byproducts.;
1: With PyBH2I in dichloromethane T=20°C; 2: With sodium hydroxide; dihydrogen peroxide in methanol; dichloromethane T=0 - 20°C; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 127, # 16 p. 5766 - 5767
