二环[2,2,2]辛烷-1,4-环己二羧酸合成路线 (共 13 条)
反应条件
1: With lithium hydroxide; water; isopropyl alcohol in tetrahydrofuran T=60 - 70°C; 2.5 h; 2: With hydrogenchloride in water T=0°C;
参考文献
ROYALTY, Susan Marie; BURNS, James Ford; SCICINSKI, Jan Jozef; FOGLESONG, Robert James; JAGDMANN, JR., Gunnar Erik; GRIFFIN, Kellee Renee; DYAKONOV, Tatyana; MIDDLEMISS, David
Patent: WO2006/12441 A1, 2006 ;
Location in patent: Page/Page column 33-34 ;
WO 2006/012441 A1
反应条件
potassium hydroxide in ethanol
参考文献
Journal of the American Chemical Society, , vol. 92, p. 1582 - 1586
反应条件
1: aq. HCl 2: N2H4*H2O, KOH / bis-(2-hydroxy-ethyl) ether 3: KMnO4, aq. KOH View Scheme
参考文献
Journal of the American Chemical Society, , vol. 86, p. 5183 - 5188
反应条件
1: N2H4*H2O, KOH / bis-(2-hydroxy-ethyl) ether 2: KMnO4, aq. KOH View Scheme
参考文献
Journal of the American Chemical Society, , vol. 86, p. 5183 - 5188
反应条件
potassium hydroxide in methanol Heating;
参考文献
Geivandov, R.Kh.; Kovshev, E.I.
Journal of Organic Chemistry USSR (English Translation), 1981 , vol. 17, p. 461 - 470
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 3 p. 543 - 553
反应条件
potassium hydroxide; potassium permanganate
参考文献
Journal of the American Chemical Society, , vol. 86, p. 5183 - 5188
反应条件
1: 90 percent / H2 / Pd/C, (10 percent) / ethyl acetate 2: 82 percent / aq. potassium hydroxide (70 percent) / methanol / Heating View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 17, p. 461 - 470
Zhurnal Organicheskoi Khimii, , vol. 17, # 3 p. 543 - 553
反应条件
1: 38 percent / lead tetraacetate / pyridine; benzene / 3 h / 80 °C 2: 90 percent / H2 / Pd/C, (10 percent) / ethyl acetate 3: 82 percent / aq. potassium hydroxide (70 percent) / methanol / Heating View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 17, p. 461 - 470
Zhurnal Organicheskoi Khimii, , vol. 17, # 3 p. 543 - 553
反应条件
barium dihydroxide in methanol; water 18 h; Ambient temperature;
参考文献
Australian Journal of Chemistry, , vol. 39, p. 2061 - 2066
反应条件
3: Raney Ni 4: sodium hydroxide View Scheme
参考文献
Journal of the American Chemical Society, , vol. 133, # 10 p. 3570 - 3581