4-氯-2,6-吡啶二羰基二氯合成路线 （共 33 条）
反应条件
thionyl chloride in chlorobenzene
3.5 h; Heating;
参考文献
Cornejo, Alfonso; Fraile, Jose M.; Garcia, Jose I.; Gil, Maria J.; Luis, Santiago V.; Martinez-Merino, Victor; Mayoral, Jose A.
Journal of Organic Chemistry, 2005 , vol. 70, # 14 p. 5536 - 5544
反应条件
thionyl chloride in N,N-dimethyl-formamide
T=76°C;
参考文献
Picot, Alexandre; Feuvrie, Christophe; Barsu, Cyril; Malvolti, Floriane; Le Guennic, Boris; Le Bozec, Hubert; Andraud, Chantal; Toupet, Loic; Maury, Olivier
Tetrahedron, 2008 , vol. 64, # 2 p. 399 - 411
反应条件
oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane
T=-10 - 20°C; 72 h; Inert atmosphere;
参考文献
Mitsui, Kazuhiko; Parquette, Jon R.
Synthesis, 2009 , # 5 p. 713 - 714
反应条件
1: aqueous ethylamine
2: SOCl2
View Scheme
参考文献
Markees
Journal of Organic Chemistry, 1958 , vol. 23, p. 1030
参考文献
Markees
Journal of Organic Chemistry, 1958 , vol. 23, p. 1030
参考文献
Markees
Journal of Organic Chemistry, 1958 , vol. 23, p. 1030
参考文献
Markees
Journal of Organic Chemistry, 1958 , vol. 23, p. 1030
反应条件
1: water
2: aq. ammonia / 24 h / 150 °C / bomb
View Scheme
参考文献
Bradshaw, J. S.; Maas, G. E.; Lamb, J. D.; Izatt, R. M.; Christensen J. J.
Journal of the American Chemical Society, 1980 , vol. 102, # 2 p. 467 - 474
反应条件
2: 64 percent / NaBH4 / ethanol / 16 h / Heating
3: 65 percent / methanesulfonyl chloride, Et3N / CH2Cl2; CHCl3 / 36 h / 20 °C
View Scheme
参考文献
Bridger, Gary J.; Skerlj, Renato T.; Padmanabhan, Sreenivasan; Martellucci, Stephen A.; Henson, Geoffrey W.; Struyf, Sofie; Witvrouw, Myriam; Schols, Dominique; De Clercq, Erik
Journal of Medicinal Chemistry, 1999 , vol. 42, # 19 p. 3971 - 3981
反应条件
3: hydrolysis
4: thionyl chloride / dimethylformamide
5: 42.9 percent / benzene / 48 h / 50 °C
View Scheme
参考文献
Bradshaw, J. S.; Maas, G. E.; Lamb, J. D.; Izatt, R. M.; Christensen J. J.
Journal of the American Chemical Society, 1980 , vol. 102, # 2 p. 467 - 474
