2-氟-3,4-二氢-1(2H)-萘酮合成路线 （共 30 条）
反应条件
tri-tert-butyl phosphine; tetra-n-butylammonium difluorotriphenylsilicate(IV); bis(dibenzylideneacetone)-palladium(0) in toluene
T=90°C; 0.333333 h;
参考文献
Guo, Yong; Twamley, Brendan; Shreeve, Jean'Ne M.
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 8 p. 1716 - 1722
反应条件
triethylamine tris(hydrogen fluoride) in acetonitrile
anodic oxidation;
参考文献
Laurent, Eliane; Tardivel, Robert; Thiebault, Hugues
Tetrahedron Letters, 1983 , vol. 24, # 9 p. 903 - 906
反应条件
triethylamine in cyclohexane
T=30°C; 15 h; Irradiation; Yield given. Yields of byproduct given;
参考文献
Sket, B.; Zupancic, N.; Zupan, M.
Journal of Fluorine Chemistry, 1989 , vol. 45, p. 313 - 321
反应条件
in chloroform
T=0°C;
参考文献
Ben-David, Iris; Mishani, Eyal; Rozen, Shlomo
Journal of Organic Chemistry, 1998 , vol. 63, # 14 p. 4632 - 4635
反应条件
tri-tert-butyl phosphine; tetra-n-butylammonium difluorotriphenylsilicate(IV); bis(dibenzylideneacetone)-palladium(0) in toluene
T=90°C; 0.333333 h;
参考文献
Guo, Yong; Twamley, Brendan; Shreeve, Jean'Ne M.
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 8 p. 1716 - 1722
反应条件
in chloroform
T=0°C; 0.5 h;
参考文献
Ben-David, Iris; Mishani, Eyal; Rozen, Shlomo
Journal of Organic Chemistry, 1998 , vol. 63, # 14 p. 4632 - 4635
反应条件
1: N-fluoro-2,6-dichloropyridinium tetrafluoroborate / acetonitrile / Heating
2: aq. HCl / acetonitrile
View Scheme
参考文献
Pravst, Igor; Zupan, Marko; Stavber, Stojan
Synthesis, 2005 , # 18 art. no. T07205SS, p. 3140 - 3146
反应条件
1: With cesium fluoroxysulphate in acetonitrile
Heating;
2: With hydrogenchloride in acetonitrile
Title compound not separated from byproducts;
参考文献
Pravst, Igor; Zupan, Marko; Stavber, Stojan
Synthesis, 2005 , # 18 art. no. T07205SS, p. 3140 - 3146
反应条件
sodium hexamethyldisilazane
1.) ether, -78 deg C, 2.) 20 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Davis, Franklin A.; Han, Wei
Tetrahedron Letters, 1991 , vol. 32, # 13 p. 1631 - 1634
反应条件
hydrogenchloride; sodium carbonate; N-fluorobislt;(trifluoromethyl)sulfonylgt;imide
1.) CH2Cl2, room temp., 5 h, 2.) CH2Cl2; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ying; DesMarteau; Gotoh
Tetrahedron, 1996 , vol. 52, # 1 p. 15 - 22
