2-(4-溴苯基)-2-氧代乙酸合成路线 （共 24 条）
反应条件
1: With potassium permanganate; sodium hydroxide in water
T=50°C; 0.333333 h;
2: With hydrogenchloride in water
参考文献
Jin, Zhe; Yang, Liu; Liu, Si-Jie; Wang, Jian; Li, Shuo; Lin, Huang-Quan; Wan, David Chi Cheong; Hu, Chun
Archives of Pharmacal Research, 2010 , vol. 33, # 10 p. 1641 - 1649
反应条件
potassium hydroxide; potassium permanganate in water
T=25°C; Rate constant;
参考文献
Lee, Donald G.; Chen, Tao
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 5341 - 5345
反应条件
water; sodium hydroxide in tetrahydrofuran
6 h; Reflux;
参考文献
Shirai, Tomohiko; Ito, Hajime; Yamamoto, Yasunori
Angewandte Chemie - International Edition, 2014 , vol. 53, # 10 p. 2658 - 2661
Angew. Chem., 2014 , vol. 126, # 10 p. 2696 - 2699,4
反应条件
aluminium trichloride in carbon disulfide
参考文献
Adlerova,E. et al.
Collection of Czechoslovak Chemical Communications, 1964 , vol. 29, p. 97 - 120
反应条件
1.1: magnesium / tetrahydrofuran / 1 h / 20 °C
1.2: 1 h / -78 - -10 °C
2.1: sodium hydroxide; water / tetrahydrofuran / 6 h / |Reflux
View Scheme
参考文献
Shirai, Tomohiko; Ito, Hajime; Yamamoto, Yasunori
Angewandte Chemie - International Edition, 2014 , vol. 53, # 10 p. 2658 - 2661
Angew. Chem., 2014 , vol. 126, # 10 p. 2696 - 2699,4
反应条件
sodium hydroxide
0.0166667 h; microwave irradiation;
参考文献
Moghaddam, Firouz Matloubi; Mirjafary, Zohreh; Saeidian, Hamdollah; Javan, Marjan Jebeli
Synlett, 2008 , # 6 p. 892 - 896
参考文献
Kroehnke
Chemische Berichte, 1947 , vol. 80, p. 298,310
反应条件
sodium hydroxide; water
参考文献
Wislicenus; Elvert
Chemische Berichte, 1908 , vol. 41, p. 4132
反应条件
potassium permanganate
参考文献
Collet
Bulletin de la Societe Chimique de France, 1899 , vol. <3> 21, p. 67
反应条件
1: concentrated hydrochloric acid
2: water; NaOH
View Scheme
参考文献
Wislicenus; Elvert
Chemische Berichte, 1908 , vol. 41, p. 4132
