反应条件
1: 72 percent / benzoyl chloride / 2 h / 20 °C
2: 75 percent / Et3N, H2 / Pd/C / tetrahydrofuran / Ambient temperature
3: 69 percent / NaHCO3, iodine, potassium iodide / H2O; CH2Cl2
4: 72 percent / H2, Et3N / Adams' platinum oxide / methanol / 0.75 h / 20 °C
5: 56 percent / acetic acid / 20 °C
6: 80 percent / sodium borohydride, Et3N / CHCl3; methanol
7: aq. KOH / 16 h / 25 °C
8: H2O / 37 °C / pH 8.25; cosynthetase; Vmax, t1/2
View Scheme
参考文献
Battersby, Alan R.; Fookes, Christopher J. R.; Gustafson-Potter, Kerstin E.; McDonald, Edward; Matcham, George W. J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 10 p. 2427 - 2444