N-(1,4-苯并二烷-2-羰基)哌嗪合成路线 （共 8 条）
反应条件
1: 2,3-dihydro-1,4-benzodioxin-2-carboxylic acid With N-bromosuccinmide; triphenylphosphine in dichloromethane T=0 - 5°C; 0.25 h; 2: piperazine With pyridine in dichloromethane T=20°C; 0.5 h;
参考文献
Bandgar; Bettigeri
Synthetic Communications, 2004 , vol. 34, # 16 p. 2917 - 2924
参考文献
Chou, Wen-Chih; Tan, Chang-Wei; Chen, Shyh-Fong; Ku, Hao
Journal of Organic Chemistry, 1998 , vol. 63, # 26 p. 10015 - 10017
参考文献
Organic Preparations and Procedures International, , vol. 35, # 6 p. 603 - 608
反应条件
1: 85 percent / potassium hydroxide; polyethylene glycol-400; potassium carbonate / toluene / 3.75 h / Heating 2: 65 percent / 6 h / 70 - 80 °C View Scheme
参考文献
Organic Preparations and Procedures International, , vol. 35, # 6 p. 603 - 608
参考文献
Tetrahedron Letters, , vol. 40, # 17 p. 3419 - 3422
反应条件
1: 2 h / 110 °C 2: 5 h / 110 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 40, # 17 p. 3419 - 3422
反应条件
in butan-1-ol 5 h; Heating;
参考文献
Kumaraswamy; Das; Jena, Nivedita
Organic Preparations and Procedures International, 2003 , vol. 35, # 6 p. 603 - 608
反应条件
in butan-1-ol 3.5 h; Heating;
参考文献
Campbell; Davey; Hardstone; Lewis; Palmer
Journal of Medicinal Chemistry, 1987 , vol. 30, # 1 p. 49 - 57
