2-羟基-3-苯基-2-环己酮合成路线 （共 24 条）
反应条件
copper diacetate; acetic acid in methanol
T=90°C;
参考文献
Feigenbaum, Alexandre; Pete, Jean-Pierre; Scholler, Denise
Journal of Organic Chemistry, 1984 , vol. 49, # 13 p. 2355 - 2360
反应条件
water; N-ethyl-N,N-diisopropylamine; triphenylphosphine; palladium diacetate in N,N-dimethyl-formamide
0.166667 h; microwave irradiation, power 50 W;
参考文献
Garg, Neeraj; Larhed, Mats; Hallberg, Anders
Journal of Organic Chemistry, 1998 , vol. 63, # 12 p. 4158 - 4162
反应条件
boron tribromide in dichloromethane
1.) -78 deg C, 1 h, 2.) -12 deg C, 3 h;
参考文献
Garg, Neeraj; Larhed, Mats; Hallberg, Anders
Journal of Organic Chemistry, 1998 , vol. 63, # 12 p. 4158 - 4162
反应条件
1: triethylamine / CH2Cl2 / 0 - 20 °C
2: sodium acetate; palladium acetate; poly(ethylene glycol) / acetonitrile; H2O / 0.33 h / 150 °C / microwave irradiation
View Scheme
参考文献
Svennebring, Andreas; Garg, Neeraj; Nilsson, Peter; Hallberg, Anders; Larhed, Mats
Journal of Organic Chemistry, 2005 , vol. 70, # 12 p. 4720 - 4725
反应条件
copper diacetate; iodine in acetic acid
15 h; Heating;
参考文献
Horiuchi, C. Akira; Kiyomiya, Hiroshi; Takahashi, Masaaki; Suzuki, Yasuto
Synthesis, 1989 , # 10 p. 785 - 786
反应条件
1: 86 percent / iPr2NEt, Ph3P, H2O / Pd(OAc)2 / dimethylformamide / 16 h / 100 °C
2: 84 percent / BBr3 / CH2Cl2 / 1.) -78 deg C, 1 h, 2.) -12 deg C, 3 h
View Scheme
参考文献
Garg, Neeraj; Larhed, Mats; Hallberg, Anders
Journal of Organic Chemistry, 1998 , vol. 63, # 12 p. 4158 - 4162
反应条件
1: 42 percent / p-TsOH*H2O / benzene / 16 h / Heating
2: 86 percent / iPr2NEt, Ph3P, H2O / Pd(OAc)2 / dimethylformamide / 16 h / 100 °C
3: 84 percent / BBr3 / CH2Cl2 / 1.) -78 deg C, 1 h, 2.) -12 deg C, 3 h
View Scheme
参考文献
Garg, Neeraj; Larhed, Mats; Hallberg, Anders
Journal of Organic Chemistry, 1998 , vol. 63, # 12 p. 4158 - 4162
反应条件
1: 86 percent / iPr2NEt, Ph3P, H2O / Pd(OAc)2 / dimethylformamide / 16 h / 100 °C
2: 84 percent / BBr3 / CH2Cl2 / 1.) -78 deg C, 1 h, 2.) -12 deg C, 3 h
View Scheme
参考文献
Garg, Neeraj; Larhed, Mats; Hallberg, Anders
Journal of Organic Chemistry, 1998 , vol. 63, # 12 p. 4158 - 4162
反应条件
sodium acetate; palladium diacetate; ethylene glycol; poly(ethylene glycol) in water; acetonitrile
T=150°C; 0.333333 h; microwave irradiation;
参考文献
Svennebring, Andreas; Garg, Neeraj; Nilsson, Peter; Hallberg, Anders; Larhed, Mats
Journal of Organic Chemistry, 2005 , vol. 70, # 12 p. 4720 - 4725
反应条件
sodium acetate; palladium diacetate; ethylene glycol; poly(ethylene glycol) in water; acetonitrile
T=150°C; 0.333333 h; microwave irradiation;
参考文献
Svennebring, Andreas; Garg, Neeraj; Nilsson, Peter; Hallberg, Anders; Larhed, Mats
Journal of Organic Chemistry, 2005 , vol. 70, # 12 p. 4720 - 4725
