(1-苯基-1H-吡唑-4-基)甲醇合成路线 （共 9 条）
反应条件
sodium hydroxide; sodium tetrahydroborate in methanol T=50 - 60°C; 1 h;
参考文献
Khan, Misbahul Ain; Ribeiro, Jorge
Polish Journal of Chemistry, 1987 , vol. 61, # 4-6 p. 569 - 572
反应条件
lithium aluminium tetrahydride in diethyl ether 7 h; Heating;
参考文献
Menozzi; Schenone; Mosti; Mattioli
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 4 p. 997 - 1002
反应条件
1: 59 percent / acetic acid / ethanol / 2 h / Heating 2: 94 percent / LiAlH4 / diethyl ether / 7 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 30, # 4 p. 997 - 1002
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Journal of the Chemical Society, , p. 1819,1821
反应条件
1: acetic acid 2: aqueous K2CO3 View Scheme
参考文献
Journal of the Chemical Society, , p. 2293,2295
反应条件
1: ZnCl2; petroleum ether / unter Einleiten von HCl und konz. H2SO4 2: acetic acid 3: aqueous K2CO3 View Scheme
参考文献
Journal of the Chemical Society, , p. 2293,2295
反应条件
1: 48percent hydrobromic acid, acetic acid / 15 h / Heating 2: dimethylsulfoxide / 0.17 h / Ambient temperature 3: 95 percent / aq. KOH / ethanol / 10 h / Heating View Scheme
参考文献
Menozzi; Schenone; Mosti; Mattioli
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 4 p. 997 - 1002
反应条件
thionyl chloride in dichloromethane T=20°C; 1 h;
参考文献
ARGENTA DISCOVERY LIMITED; ASTRAZENECA AB
Patent: WO2009/153536 A1, 2009 ;
Location in patent: Page/Page column 43 ;
WO 2009/153536 A1
反应条件
1: 48percent hydrobromic acid, acetic acid / 15 h / Heating
2: dimethylsulfoxide / 0.17 h / Ambient temperature
View Scheme
参考文献
Menozzi; Schenone; Mosti; Mattioli
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 4 p. 997 - 1002
