(R)-3-(吡咯烷-2-基)吡啶合成路线 (共 4 条)
反应条件
sodium cyanoborohydride 1.) aq. MeOH, 15 min, 2.) aq. EtOH; Yield given. Multistep reaction;
参考文献
Jacob III; Benowitz; Copeland; Risner; Cone
Journal of Pharmaceutical Sciences, 1988 , vol. 77, # 5 p. 396 - 400
反应条件
lithium hexamethyldisilazane in tetrahydrofuran T=-78 - 20°C;
参考文献
Girard; Robins; Villieras; Lebreton
Tetrahedron Letters, 2000 , vol. 41, # 48 p. 9245 - 9249
反应条件
1: Et3N / diethyl ether / 20 °C 2: LiAlH4 / tetrahydrofuran / 0 °C View Scheme
参考文献
Girard; Robins; Villieras; Lebreton
Tetrahedron Letters, 2000 , vol. 41, # 48 p. 9245 - 9249
参考文献
Spaeth; Hicks; Zajic
Chemische Berichte, 1935 , vol. 68, p. 1389