6-甲基咪唑并[1,2-A]砒啶-2-羧酸乙酯合成路线 （共 3 条）
反应条件
in ethanol 6 h; Heating;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 11 p. 2790 - 2794
反应条件
hydrazine hydrate; palladium on activated charcoal in ethanol 0.166667 h; Heating;
参考文献
Rees, Charles W.; Smith, David I.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 1159 - 1164
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran
T=5°C; 1 h;
2: With ethyl acetate in tetrahydrofuran
3: With water in tetrahydrofuran; dichloromethane; ethyl acetate
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2008/84223 A2, 2008 ;
Location in patent: Page/Page column 424 ;
WO 2008/084223 A2
