2-羰基-1 ,2,3,4-四氢喹啉-6-羧酸合成路线 （共 4 条）
反应条件
n-butyllithium; ammonium chloride in tetrahydrofuran
参考文献
US2004/122001 A1, ;
US 20040122001 A1
反应条件
sodium hydroxide T=60 - 70°C; 3 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 34, # 2 p. 682 - 693
反应条件
1: 2 h / 80 - 90 °C 2: aq. NaOH / 3 h / 60 - 70 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 34, # 2 p. 682 - 693
反应条件
1: Et3N / dimethylformamide / 1 h / Ambient temperature
2: dimethylformamide / 3 h / Ambient temperature
3: 91 percent / H2 / 10 percent Pd-C / ethanol; H2O / 45 - 50 °C
View Scheme
参考文献
Tominaga; Yo; Ogawa; Yamashita; Yabuuchi; Nakagawa
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 2 p. 682 - 693
