4-甲基-1-苯基-2,6,7-三氧杂双环[2.2.2]辛烷合成路线 （共 4 条）
反应条件
boron trifluoride diethyl etherate in dichloromethane
T=25°C; 24 h;
参考文献
Kanoh, Shigeyoshi; Naka, Masashi; Nishimura, Tomonari; Motoi, Masatoshi
Tetrahedron, 2002 , vol. 58, # 35 p. 7049 - 7064
反应条件
in N,N-dimethyl-formamide
T=20°C; 2 h; Molecular sieve;
参考文献
Tange, Seiko; Fukuhara, Tsuyoshi; Hara, Shoji
Synthesis, 2008 , # 20 p. 3219 - 3222
反应条件
toluene-4-sulfonic acid
T=100°C; P=0.1 Torr;
参考文献
McClelland, Robert A.; Gedge, Sherrin; Bohonek, Jon
Journal of Organic Chemistry, 1981 , vol. 46, # 5 p. 886 - 891
反应条件
1: 64 percent / ethyl carbonate, KOH / ethanol / 0.25 h / Heating
2: 70 percent / pyridine / CH2Cl2
3: 41 percent / BF3*Et2O / CH2Cl2 / 24 h / Ambient temperature
View Scheme
参考文献
Rakus, Klaus; Verevkin, Sergey P.; Peng, Wei-Hong; Beckhaus, Hans-Dieter; Ruechardt, Christoph
Liebigs Annalen, 1995 , # 12 p. 2059 - 2068
