反应条件
1: diphenyl carbonate, NaHCO3 / dimethylformamide / 4 h / 100 °C
2: 88 percent / NaH / N,N-dimethyl-acetamide / 1.) r.t., 2 h, 2.) r.t., 1.5 h
3: 73 percent / Raney nickel / H2O / 1 h / 75 °C
4: 1-methylpyrrolidine / acetonitrile / 1 h / Ambient temperature
5: 1.) TFAA / 1.) MeCN, 30 min, 2.) MeCN, 0 deg C, 3 h
6: 94 percent / NH4OH, H2O / dioxane / 24 h / 50 °C
View Scheme
参考文献
Miah, Anwar; Reese, Colin B.; Song, Quanlai; Sturdy, Zoe; Neidle, Stephen; Simpson, Ian J.; Read, Martin; Rayner, Emma
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 19 p. 3277 - 3283
