1-O,2-O-异亚丙基-5-脱氧-alpha-D-呋喃葡萄糖合成路线 （共 16 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Urban, Ernst; Noe, Christian R.
Farmaco, 2003 , vol. 58, # 3 p. 243 - 258
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in 1,4-dioxane; toluene
2 h; Heating;
参考文献
Tarnowski, Andrej; Retz, Oliver; Baer, Thomas; Schmidt, Richard R.
European Journal of Organic Chemistry, 2005 , # 6 p. 1129 - 1141
反应条件
1: 76 percent / tetrahydrofuran / 2 h / Heating
2: 71 percent / Bu3SnH; AIBN / dioxane; toluene / 2 h / Heating
View Scheme
参考文献
Tarnowski, Andrej; Retz, Oliver; Baer, Thomas; Schmidt, Richard R.
European Journal of Organic Chemistry, 2005 , # 6 p. 1129 - 1141
反应条件
1: potassium hexamethyldisilazide / tetrahydrofuran; toluene / 3 h / Ambient temperature
2: 1) 2-methyl-2-butene, borane-THF, 2) aq. NaOH, H2O2 / 1) THF, 0 deg C, 1 h, 2) RT
View Scheme
参考文献
Tsui, Hon-Chung; Paquette, Leo A.
Journal of Organic Chemistry, 1998 , vol. 63, # 26 p. 9968 - 9977
反应条件
1: 89 percent / DMAP, triethylamine / CH2Cl2 / 3 h / 20 °C
2: 87 percent / aq. acetic acid / 24 h / 20 °C
3: 1) Ph3P, imidazole, iodine, 2) aq. NaOH / 1) toluene, 80 deg C, 3 h, 2) methanol, RT, 30 min
4: 1) 2-methyl-2-butene, borane-THF, 2) aq. NaOH, H2O2 / 1) THF, 0 deg C, 1 h, 2) RT
View Scheme
参考文献
Tsui, Hon-Chung; Paquette, Leo A.
Journal of Organic Chemistry, 1998 , vol. 63, # 26 p. 9968 - 9977
反应条件
1: 78 percent / acid
2: 95 percent / pyridine
3: n-Bu3SnH; AIBN
4: 85 percent / LiAlH4 / tetrahydrofuran
View Scheme
参考文献
Urban, Ernst; Noe, Christian R.
Farmaco, 2003 , vol. 58, # 3 p. 243 - 258
反应条件
1: 95 percent / pyridine
2: n-Bu3SnH; AIBN
3: 85 percent / LiAlH4 / tetrahydrofuran
View Scheme
参考文献
Urban, Ernst; Noe, Christian R.
Farmaco, 2003 , vol. 58, # 3 p. 243 - 258
反应条件
1: SO2Cl2, pyridine / 4 h / -40 - 0 °C
2: tributyltin hydride, α,α-azoisobisbutyronitrile (AIBN) / toluene / 18 h / Heating
3: LAH / tetrahydrofuran / 24 h / Heating
View Scheme
参考文献
Gurjar; Mainkar
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 12 p. 1081 - 1082
反应条件
1: tributyltin hydride, α,α-azoisobisbutyronitrile (AIBN) / toluene / 18 h / Heating
2: LAH / tetrahydrofuran / 24 h / Heating
View Scheme
参考文献
Gurjar; Mainkar
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 12 p. 1081 - 1082
反应条件
1: 15 h / Heating; in the presence of acid
2: SO2Cl2, pyridine / 4 h / -40 - 0 °C
3: tributyltin hydride, α,α-azoisobisbutyronitrile (AIBN) / toluene / 18 h / Heating
4: LAH / tetrahydrofuran / 24 h / Heating
View Scheme
参考文献
Gurjar; Mainkar
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 12 p. 1081 - 1082
