2-羟基-3-异丙基苯甲酸合成路线 （共 11 条）
反应条件
1: o-isopropyl phenol With sodium methylate in methanol T=180°C; 4 h; γ-IrradiationSimultaneous removal of methanol by distillation; 2: carbon dioxide T=200°C; Kolbe-Schmitt Reaction; P=4413.43 Torr; 2 h; 3: With sulfuric acid in water
参考文献
Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo
Patent: EP1600435 A1, 2005 ;
Location in patent: Page/Page column 8 ;
反应条件
1: With silver nitrate; sodium hydroxide in ethanol T=20°C; 2: With hydrogenchloride in water T=10 - 15°C; pH=2;
参考文献
WO2009/140275 A1, ;
Page/Page column 18-19 ;
反应条件
1: 60.7 percent / HCl / ethyl acetate / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 43, # 7 p. 1519 - 1540
参考文献
Journal of the American Chemical Society, , vol. 56, p. 2054
Journal of Organic Chemistry, , vol. 2, p. 253,255
参考文献
Journal of Organic Chemistry, , vol. 2, p. 253,256
反应条件
1: boron fluoride / Erwaermen des Reaktionsprodukts mit Methanol und Schwefelsaeure 2: ethanolic NaOH-solution View Scheme
参考文献
Journal of Organic Chemistry, , vol. 2, p. 253,256
参考文献
Gazzetta Chimica Italiana, , vol. 16, p. 114
反应条件
1: diluted sulfuric acid; nitrous acid / Diazotization 2: sodium / 150 °C View Scheme
参考文献
Gazzetta Chimica Italiana, , vol. 16, p. 114
反应条件
Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 43, # 7 p. 1519 - 1540
参考文献
Journal of Organic Chemistry, , vol. 2, p. 253,256
