1-氯-3,5-二甲氧基苯合成路线 （共 65 条）
反应条件
hydrogenchloride; hypophosphorous ether; sodium nitrite in 1,4-dioxane; water T=0°C; 20 h;
参考文献
Sargent, Melvyn V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 1095 - 1098
反应条件
copper dichloride in methanol T=90°C;
参考文献
Murphy, Jaclyn M.; Liao, Xuebin; Hartwig, John F.
Journal of the American Chemical Society, 2007 , vol. 129, # 50 p. 15434 - 15435
反应条件
palladium (II) trifluoroacetate; trifluoroacetic acid in dimethyl sulfoxide; N,N-dimethyl-formamide T=70°C; 24 h;
参考文献
Dickstein, Joshua S.; Curto, John M.; Gutierrez, Osvaldo; Mulrooney, Carol A.; Kozlowski, Marisa C.
Journal of Organic Chemistry, 2013 , vol. 78, # 10 p. 4744 - 4761
反应条件
sodium methylate in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=120°C; 1 h;
参考文献
Tetrahedron, , vol. 39, # 1 p. 193 - 198
反应条件
in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=120°C;
参考文献
Tetrahedron, , vol. 39, # 1 p. 193 - 198
反应条件
[bis(acetoxy)iodo]benzene; sodium chloride 0.5 h;
参考文献
Karade; Tiwari; Huple; Siddiqui
Journal of Chemical Research, 2006 , # 6 p. 366 - 368
反应条件
1: 87 percent / hydrogen chloride gas / 25 - 30 °C 2: 92 percent / 1.) conc. hydrochloric acid, sodium nitrite, 2.) phosphinous acid / dioxane; H2O / 20 h / 0 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1095 - 1098
反应条件
sodium hydroxide T=30°C;
参考文献
Journal of the Chemical Society, , p. 1433
反应条件
(i) HCl, (ii) pentyl nitrite, CHCl3, (iii) aq. HCl; Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 31, p. 2459 - 2467
反应条件
sodium hydroxide in N,N-dimethyl acetamide T=25°C; Rate constant;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 66, # 5 p. 1583 - 1585
