2-乙炔基-α,α,α-三氟甲苯合成路线 （共 15 条）
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 0.166667 h;
参考文献
Nguyen, Ngoc-Ha; Apriletti, James W.; Baxter, John D.; Scanlan, Thomas S.
Journal of the American Chemical Society, 2005 , vol. 127, # 13 p. 4599 - 4608
反应条件
n-butyllithium in diethyl ether 1.4 h;
参考文献
Kodaira, Kazuo; Okuhara, Kunio
Bulletin of the Chemical Society of Japan, 1988 , vol. 61, # 5 p. 1625 - 1632
反应条件
potassium hydroxide in diethyl ether; water T=180 - 220°C;
参考文献
Mesnard, Danielle; Bernadou, Francoise; Miginiac, Leone
Journal of Chemical Research, Miniprint, 1981 , # 9 p. 3216 - 3245
反应条件
1: 46 percent / PdCl2(PPh3)2; CuI; diethylamine / 20 °C 2: 29 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.17 h / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 127, # 13 p. 4599 - 4608
反应条件
1: 45 percent / P2O5 / benzene / 4 h / Heating 2: Br2 / diethyl ether / 2 h / -10 °C 3: 47 percent / KOH / H2O; diethyl ether / 180 - 220 °C View Scheme
参考文献
Journal of Chemical Research, Miniprint, , # 9 p. 3216 - 3245
反应条件
1: Br2 / diethyl ether / 2 h / -10 °C 2: 47 percent / KOH / H2O; diethyl ether / 180 - 220 °C View Scheme
参考文献
Journal of Chemical Research, Miniprint, , # 9 p. 3216 - 3245
参考文献
Journal of the American Chemical Society, , vol. 85, p. 3492 - 3496
反应条件
2: KHSO4 3: (i) Br2, (ii) KOH 4: KOH View Scheme
参考文献
Journal of the American Chemical Society, , vol. 85, p. 3492 - 3496
反应条件
1: 1.) Mg / 1.) Et2O, reflux; 2.) 20 deg C, 12 h; reflux, 2 h 2: 45 percent / P2O5 / benzene / 4 h / Heating 3: Br2 / diethyl ether / 2 h / -10 °C 4: 47 percent / KOH / H2O; diethyl ether / 180 - 220 °C View Scheme
参考文献
Journal of Chemical Research, Miniprint, , # 9 p. 3216 - 3245
反应条件
1: 1.) n-C4H9Li 2: n-C4H9Li View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 23, p. 497
