2-(氯甲基)-5-苯基-1,3,4-噻二唑合成路线 （共 4 条）
反应条件
thiourea in tetrahydrofuran
T=120 - 150°C; Sealed tube;
参考文献
Padmavathi; Dinneswara Reddy; Nagi Reddy; Mahesh
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1367 - 1373
反应条件
Lawesson's reagent in toluene
T=110°C; 2 h;
参考文献
Cao, Song; Wei, Na; Zhao, Chuanmeng; Li, Lina; Huang, Qingchun; Qian, Xuhong
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 8 p. 3120 - 3125
反应条件
1: trichlorophosphate / Reflux
2: thiourea / tetrahydrofuran / 120 - 150 °C / Sealed tube
View Scheme
参考文献
Padmavathi; Dinneswara Reddy; Nagi Reddy; Mahesh
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1367 - 1373
参考文献
Kristinsson,H.
Synthesis, 1979 , p. 102 - 103
