5-溴-1,3-二甲基尿嘧啶合成路线 （共 49 条）
反应条件
sodium hydrogencarbonate in water
6 h; Heating;
参考文献
Chauhan; Kohli; Rao; Gulati
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 6 p. 539 - 544
反应条件
1: sodium ethanolate / ethanol / 72 h / 20 °C
2: hydrogen bromide / 1 h / Reflux
View Scheme
参考文献
Sajiki, Hironao; Iida, Yusuke; Ikawa, Kanoko; Sawama, Yoshinari; Monguchi, Yasunari; Kitade, Yukio; Maki, Yoshifumi; Inoue, Hideo; Hirota, Kosaku
Molecules, 2012 , vol. 17, # 6 p. 6519 - 6546
反应条件
sodium peroxodisulphate in water
T=80°C; 5 h;
参考文献
Itahara, Toshio; Nishino, Akihiro
Chemistry Letters, 1991 , # 12 p. 2203 - 2204
反应条件
copper(I) bromide; lithium tert-butylate in N,N-dimethyl-formamide
1 h; Reflux; regioselective reaction;
参考文献
Cheng, Chien; Shih, Yu-Chiao; Chen, Hui-Ting; Chien, Tun-Cheng
Tetrahedron, 2013 , vol. 69, # 4 p. 1387 - 1396
反应条件
copper(I) bromide; lithium tert-butylate in N,N-dimethyl-formamide
1 h; Reflux; regioselective reaction;
参考文献
Cheng, Chien; Shih, Yu-Chiao; Chen, Hui-Ting; Chien, Tun-Cheng
Tetrahedron, 2013 , vol. 69, # 4 p. 1387 - 1396
参考文献
Seki; Matsuda; Bando; Ohkura
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 12 p. 4737 - 4748
反应条件
potassium carbonate; tetra(n-butyl)ammonium hydrogensulfate in N,N-dimethyl-formamide
T=0 - 10°C;
参考文献
Kumar; Chimni
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 12 p. 1079 - 1081
反应条件
in 1-methyl-pyrrolidin-2-one
T=130°C; 0.05 h; microwave irradiation;
参考文献
Fang, Woei-Ping; Cheng, Yuh-Tsyr; Cheng, Yann-Ru; Cherng, Yie-Jia
Tetrahedron, 2005 , vol. 61, # 12 p. 3107 - 3113
反应条件
tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate in N,N-dimethyl-formamide
T=0 - 10°C;
参考文献
Kumar, Subodh; Chimni, Swapandeep Singh
Journal of Chemical Research, Miniprint, 1992 , # 1 p. 343 - 359
