乙基3-(2-甲氧基苯基)丙酸酯合成路线 （共 18 条）
反应条件
1: HCl / diethyl ether / Heating
2: H2 / PtO2 / ethanol
View Scheme
参考文献
Orr; Musso; Boswell; Kelley; Joyner; Davis; Baccanari
Journal of Medicinal Chemistry, 1995 , vol. 38, # 19 p. 3850 - 3856
反应条件
1: 1) piperidine, 2) conc. H2SO4 / 1) pyridine
2: hydrogen / 5percent Pd/C / ethanol
View Scheme
参考文献
Brown; Blakemore; Durant; Emmett; Ganellin; Parsons; Rawlings; Walker
European Journal of Medicinal Chemistry, 1988 , vol. 23, # 1 p. 53 - 62
反应条件
1: pyridinium chlorochromate / dichloromethane
2: sodium hydride / tetrahydrofuran
3: hydrogen; palladium on activated charcoal / ethyl acetate
View Scheme
参考文献
Mimori, Seisuke; Okuma, Yasunobu; Kaneko, Masayuki; Kawada, Koichi; Nomura, Yasuyuki; Murakami, Yasuoki; Hamana, Hiroshi
Chemistry Letters, 2013 , vol. 42, # 9 p. 1051 - 1052
反应条件
sulfuric acid; palladium; acetic acid
Hydrogenation;
参考文献
Kindler; Peschke
Archiv der Pharmazie (Weinheim, Germany), 1933 , vol. 271, p. 431,435
反应条件
1: ethyl acetate; sodium
2: palladium; sulfuric acid; acetic acid / Hydrogenation
View Scheme
参考文献
Kindler; Peschke
Archiv der Pharmazie (Weinheim, Germany), 1933 , vol. 271, p. 431,435
反应条件
1: ethyl acetate; sodium
2: palladium; sulfuric acid; acetic acid / Hydrogenation
View Scheme
参考文献
Kindler; Peschke
Archiv der Pharmazie (Weinheim, Germany), 1933 , vol. 271, p. 431,435
反应条件
hydrogenchloride; ethanol
参考文献
Lockett; Short
Journal of the Chemical Society, 1939 , p. 787,789
反应条件
1: sodium; ethanol
2: pyridine; SOCl2
3: potassium cyanide; ethanol / Erhitzen des Reaktionsprodukts mit methanol. KOH
View Scheme
参考文献
Lockett; Short
Journal of the Chemical Society, 1939 , p. 787,789
