1-(2,4-二羟基-6-甲基苯基)乙酮合成路线 (共 23 条)
反应条件
1: sodium propionate / 180 °C / Behandeln des Reaktionsprodukts mit konz. Schwefelsaeure 2: aq. NaOH solution View Scheme
参考文献
Sethna; Shah
Journal of the Indian Chemical Society, 1940 , vol. 17, p. 487,490
反应条件
1: sodium benzoate / 180 °C 2: ethanolic KOH-solution View Scheme
参考文献
Sethna; Shah
Journal of the Indian Chemical Society, 1940 , vol. 17, p. 601,603
参考文献
Shah; Shah
Journal of the Chemical Society, 1938 , p. 1424,1427
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Desai; Mavani
Proceedings - Indian Academy of Sciences, Section A, 1949 , vol. <A> 29, p. 269,270
反应条件
boron trifluoride diethyl etherate
T=80°C; 18 h;
参考文献
aRigen Pharmaceuticals, Inc.; SAIMOTO, Hiroyuki; KITA, Kiyoshi; YABU, Yoshisada; YAMAMOTO, Masaichi
Patent: EP2636663 A1, 2013 ;
Location in patent: Paragraph 0133; 0137; 0138 ;
反应条件
zinc(II) chloride in diethyl ether
T=20°C; 3 h;
参考文献
Zhou, Ting; Shi, Qian; Chen, Chin-Ho; Zhu, Hao; Huang, Li; Ho, Phong; Lee, Kuo-Hsiung
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 18 p. 6678 - 6689
反应条件
water
50 h; Heating;
参考文献
Crombie, Leslie; Games, David E.; James, Alun W. G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1996 , # 22 p. 2715 - 2724
反应条件
1: 80 percent / imidazole / dimethylformamide / 20 h / 40 °C
2: AlCl3 / CH2Cl2 / 2 h / Ambient temperature
3: n-Bu4NF / tetrahydrofuran / 0.33 h / 0 °C
View Scheme
参考文献
Tabuchi; Tajimi; Ichihara
Bioscience, Biotechnology and Biochemistry, 1994 , vol. 58, # 11 p. 1956 - 1959
参考文献
Sethna; Shah
Journal of the Indian Chemical Society, 1940 , vol. 17, p. 211,213
反应条件
aluminium trichloride; nitrobenzene
参考文献
Desai; Ekhlas
Proceedings - Indian Academy of Sciences, Section A, 1938 , # 8 p. 194,199
Show Details
Desai; Vakil
Proceedings - Indian Academy of Sciences, Section A, 1940 , vol. 12, p. 391,394
参考文献
Zak,H.; Schmidt,U.
Chemische Berichte, 1973 , vol. 106, p. 3652 - 3660