1-(2-羟基-6-甲氧基苯基)乙基-1-酮合成路线 （共 45 条）
反应条件
potassium carbonate in acetone 4 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 11 p. 2125 - 2131
反应条件
iodine 17 h; Heating / reflux;
参考文献
WO2007/70986 A1, ;
Page/Page column 17; 44; 46 ;
反应条件
1: With tetrabutyl ammonium fluoride T=20°C; 3 h; Inert atmosphere; 2: With water T=20°C;
参考文献
Tetrahedron, , vol. 68, # 1 p. 179 - 189
反应条件
bismuth trifluoromethanesulphonate in toluene T=110°C; Fries rearrangement;
参考文献
Synlett, , # 15 p. 2794 - 2796
反应条件
sodium hydroxide in ethanol Ambient temperature;
参考文献
Liebigs Annalen der Chemie, , # 8 p. 795 - 805
反应条件
titanium tetrachloride in dichloromethane 16 h; Ambient temperature;
参考文献
Tetrahedron Letters, , vol. 39, # 28 p. 4995 - 4998
反应条件
tetrabutyl ammonium fluoride T=20°C; 3 h; Inert atmosphere;
参考文献
Organic Letters, , vol. 12, # 9 p. 1956 - 1959
反应条件
iodine 9 h; Microwave irradiation;
参考文献
Chemistry - A European Journal, , vol. 19, # 24 p. 7917 - 7930
反应条件
1: 1) BuLi, 2) ZnCl2, 3) PdCl2(PPh3)2, DIBAL-H / 1) THF, -78 deg C, 2) THF, -78 deg C, 3) THF, 0 deg C to RT 2: 72 percent / TiCl4 / CH2Cl2 / 16 h / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 39, # 28 p. 4995 - 4998
反应条件
n-butyllithium; N-lithium N'-methylpiperazide in toluene 1.) 15 deg C, 20 min, 2.) 65-70 deg C;
参考文献
Synthetic Communications, , vol. 18, # 2 p. 191 - 196
