4-羟基-2(1H)-喹啉酮合成路线 （共 93 条）
参考文献
Hardman; Partridge
Journal of the Chemical Society, 1955 , p. 510,513
反应条件
trichlorophosphate 3 h; Reflux;
参考文献
Cheng, Pi; Gu, Qiong; Liu, Wei; Zou, Jian-Feng; Ou, Yang-Yong; Luo, Zhong-Yong; Zeng, Jian-Guo
Molecules, 2011 , vol. 16, # 9 p. 7649 - 7661
参考文献
Friedlaender; Weinberg
Chemische Berichte, 1882 , vol. 15, p. 2680
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Baeyer; Bloem
Chemische Berichte, 1882 , vol. 15, p. 2149
参考文献
Koller
Chemische Berichte, 1927 , vol. 60, p. 1110
反应条件
1: 93 percent / 12 h / Heating 2: 83 percent / H2 / 10percent Pd/C / acetic acid / 6 h View Scheme
参考文献
Steinschifter, Waltraud; Stadlbauer, Wolfgang
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1994 , vol. 336, # 4 p. 311 - 318
反应条件
potassium carbonate in acetone 2 h; Heating;
参考文献
Chen, Yeh-Long; Hung, Hsien-Ming; Lu, Chih-Ming; Li, Kuang-Chieh; Tzeng, Cherng-Chyi
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 24 p. 6539 - 6546
反应条件
1: 4-hydroxyquinolin-2(1H)-one With potassium carbonate in N,N-dimethyl-formamide T=90°C; 2 h; 2: CH3X, X=halide in N,N-dimethyl-formamide T=50 - 90°C;
参考文献
Guo, Li-Jun; Wei, Cheng-Xi; Jia, Jing-Hao; Zhao, Li-Ming; Quan, Zhe-Shan
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 3 p. 954 - 958
反应条件
1: sodium nitrite, aq. HCl / 0.5 h 2: 2.) aq. NaOH / 1.) acetone, reflux, 0.5 h, 2.) acetone, reflux, 0.5 h View Scheme
参考文献
Fadda; Khalil; El-Habbal
Journal of the Indian Chemical Society, 1991 , vol. 68, # 7 p. 393 - 395
反应条件
potassium hydroxide in acetone 2 h; Heating; Yields of byproduct given;
参考文献
Reisch, Johannes; Mester, Iuliu
Archiv der Pharmazie (Weinheim, Germany), 1980 , vol. 313, # 9 p. 751 - 755
反应条件
potassium hydroxide in acetone 2 h; Heating; Yields of byproduct given;
参考文献
Reisch, Johannes; Mester, Iuliu
Archiv der Pharmazie (Weinheim, Germany), 1980 , vol. 313, # 9 p. 751 - 755
