2-羟基-5-氨基-2,4,6-环庚三烯-1-酮合成路线 （共 11 条）
反应条件
Yield given. Multistep reaction;
参考文献
Menard, D.; St-Jacques M.; Bagli, J. F.
Canadian Journal of Chemistry, 1982 , vol. 60, p. 231 - 238
反应条件
hydrogen; platinum(IV) oxide in methanol
2.5 h;
参考文献
Research Foundation Itsuu Laboratory
Patent: EP1357104 A1, 2003 ;
Location in patent: Page/Page column 6-7 ;
反应条件
1.1: sodium nitrite / H2O / 0.5 h / 20 °C
1.2: 92 percent / acetic acid / H2O / 0.5 h
2.1: 97 percent / hydrogen / Pd/carbon / methanol / 2 h / 749.87 Torr
View Scheme
参考文献
Potenziano, James; Spitale, Robert; Janik, Mark E.
Synthetic Communications, 2005 , vol. 35, # 15 p. 2005 - 2016
反应条件
sulfuric acid in chloroform
T=20°C; 1 h;
参考文献
Yamamoto, Hiroshi; Hara, Atsushi; Noguchi, Ayashi; Kawamoto, Heizan; Inokawa, Saburo; Nozoe, Tetsuo
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 5 p. 1594 - 1598
参考文献
Luminex Corporation
Patent: US7867774 B2, 2011 ;
反应条件
sulfuric acid in chloroform
T=20°C;
参考文献
Yamamoto, Hiroshi; Hara, Atsushi; Noguchi, Ayashi; Kawamoto, Heizan; Inokawa, Saburo; Nozoe, Tetsuo
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 5 p. 1594 - 1598
反应条件
1: 80 percent / aq. KOH / 2-methyl-propan-2-ol / 3 h / 20 °C
2: conc. H2SO4 / CHCl3 / 20 °C
View Scheme
参考文献
Yamamoto, Hiroshi; Hara, Atsushi; Noguchi, Ayashi; Kawamoto, Heizan; Inokawa, Saburo; Nozoe, Tetsuo
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 5 p. 1594 - 1598
反应条件
sodium hydroxide; sodium dithionite
参考文献
Kato,M. et al.
Tetrahedron, 1971 , vol. 27, p. 4013 - 4020
参考文献
Sunagawa,G.; Watatani,M.
Chemical and Pharmaceutical Bulletin, 1968 , vol. 16, # 7 p. 1308 - 1315
参考文献
Nozoe et al.
Sci. Rep. Tohoku Univ., Ser. 1: Phys., Chem., Astron., 1952 , vol. # 35, p. 1895,274,281
