3-苄基-3-氮杂双环[3.1.0]己烷合成路线 （共 5 条）
反应条件
sodium bis(2-methoxyethoxy)aluminium dihydride in diethyl ether; toluene T=0°C; 4.5 h; Inert atmosphereReflux;
参考文献
F. HOFFMANN-LA ROCHE AG; HERMANN, Johannes Cornelius; KUGLSTATTER, Andreas; LUCAS, Matthew C.; PADILLA, Fernando; WANNER, Jutta; ZHANG, Xiaohu
Patent: WO2013/64445 A1, 2013 ;
Location in patent: Page/Page column 81 ;
反应条件
1: 1.5 h / 170 °C / |Cooling with ice 2: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene; diethyl ether / 4.5 h / 0 °C / |Inert atmosphere; |Reflux View Scheme
反应条件
1: Heating 2: LAH / 5 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 8 p. 2093 - 2096
反应条件
1: SOCl2 / 1 h / Heating 2: Heating 3: LAH / 5 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 8 p. 2093 - 2096
反应条件
1: aq. NaOH / 5 h 2: SOCl2 / 1 h / Heating 3: Heating 4: LAH / 5 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 8 p. 2093 - 2096
