2-(4-羟基苯氧基)乙酸甲酯合成路线 （共 10 条）
反应条件
hydrogen; palladium on activated carbon in methanol 10 h;
参考文献
BEZWADA BIOMEDICAL, LLC
Patent: US2007/135355 A1, 2007 ;
Location in patent: Page/Page column 20 ;
反应条件
1: With sodium methylate in methanol T=20°C; 1 h; 2: With hydrogenchloride in methanol; water
参考文献
INSTITUE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA
Patent: US2011/9427 A1, 2011 ;
Location in patent: Page/Page column 8 ;
反应条件
sulfuric acid Heating;
参考文献
IRM LLC
Patent: WO2007/56497 A1, 2007 ;
Location in patent: Page/Page column 41-42 ;
WO 2007/056497 A1
反应条件
1: Cs2CO3 / acetonitrile 2: H2 / Pd/C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 6 p. 1673 - 1678
反应条件
1: K2CO3 / dimethylformamide; xylene 2: AcOH / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 13 p. 1709 - 1713
反应条件
1: K2S2O8 / H2O 2: K2CO3 / dimethylformamide; xylene 3: AcOH / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 13 p. 1709 - 1713
反应条件
ammonium hydroxide Ambient temperature;
参考文献
Wimalasena, Kandatege; May, Sheldon W.
Journal of the American Chemical Society, 1987 , vol. 109, # 13 p. 4036 - 4046
反应条件
sodium hydroxide Heating;
参考文献
BEZWADA BIOMEDICAL, LLC
Patent: US2007/135355 A1, 2007 ;
Location in patent: Page/Page column 20 ;
反应条件
1: 83 percent / cc. NH4OH / Ambient temperature
2: 31 percent / 1.) LiAlH4 2.) cc. HCl / tetrahydrofuran / 1.) reflux, 12 h
View Scheme
参考文献
Wimalasena, Kandatege; May, Sheldon W.
Journal of the American Chemical Society, 1987 , vol. 109, # 13 p. 4036 - 4046
