in alkal. Loesung.Hydrogenation;

iodine in water T=22°C; 0.0833333 h; potassim iodide/chloramine T in phosphate buffer instead of iodine; tritium isotope effect;

chloro-trimethyl-silane T=20°C; 24 h;

sodium hydrogencarbonate in N,N-dimethyl-formamide; acetone T=20°C;

1: 83 percent / HCl (gas) / methanol / 4.5 h 2: 100 percent / NaOH / H2O; dioxane / 0.5 h / 20 °C 3: 96 percent / CuI; Et3N / Pd(PPh3)2Cl2 / 4 h / 20 °C 4: 79 percent / KF / dimethylformamide / 4 h / 20 °C 5: 60 percent / α-chymotrypsin; aq. NH4OAc / dimethylformamide / 12 h / 20 °C 6: 79 percent / 10percent TFA / CH2Cl2 / 1 h / 20 °C View Scheme

1: SOCl2 / 18 h / 20 °C 2: 6.92 g / Na2CO3 / methanol; toluene / 2 h / 0 °C 3: 96 percent / K2CO3; Cs2CO3 / dimethylformamide / 2 h / 20 °C 4: 88 percent / Pd(dppf)Cl2*CH2Cl2; KOAc / dimethylsulfoxide / 24 h / 80 °C 5: 93 percent / H2O2 / methanol; H2O / 0.5 h / 20 °C View Scheme

triethylamine in 1,4-dioxane; water T=20°C;

triethylamine in 1,4-dioxane; water 4 h;