13-甲基-1,4,7,10-四氧杂-13-氮杂环十五烷合成路线 （共 8 条）
反应条件
1) room temperature, 2) CH3OH, 12 h, reflux;
参考文献
Pharmazie, , vol. 45, # 2 p. 140 - 140
反应条件
sodium carbonate in acetonitrile
24 h; Heating;
参考文献
Schultz,R.A.; White,B.D.; Dishong,D.M.
Journal of the American Chemical Society, 1985 , vol. 107, p. 6659
反应条件
1: H2
2: Na2CO3
View Scheme
参考文献
Schultz, Rose Ann; Schlegel, Eric; Dishong, Dennis M.; Gokel, George W.
Journal of the Chemical Society, Chemical Communications, 1982 , # 4 p. 242 - 243
反应条件
sodium hydroxide; p-toluenesulfonyl chloride in 1,4-dioxane
参考文献
Kuo,P.-L. et al.
Tetrahedron Letters, 1978 , p. 4273 - 4276
反应条件
1: LiAlH4 / tetrahydrofuran / Heating
2: aq. HCHO
View Scheme
参考文献
Johnson,M.R. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1979 , p. 357 - 371
反应条件
1: (i) NaH, THF, (ii) /BRN= 632509/
2: LiAlH4 / tetrahydrofuran / Heating
3: aq. HCHO
View Scheme
参考文献
Johnson,M.R. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1979 , p. 357 - 371
参考文献
Johnson,M.R. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1979 , p. 357 - 371
参考文献
Schultz, Rose Ann; Schlegel, Eric; Dishong, Dennis M.; Gokel, George W.
Journal of the Chemical Society, Chemical Communications, 1982 , # 4 p. 242 - 243
