顺式-4,7-辛二烯酸乙酯合成路线 （共 7 条）
反应条件
in N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=180°C; 3 h;
参考文献
Vig, O. P.; Sharma, M. L.; Bhanot, R. K.; Malik, Neera
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. <B> 20, # 11 p. 970 - 971
反应条件
1: 90 percent / H2 / Lindlar's catalyst, quinoline / hexane
2: 90 percent / PBr3, pyridine / diethyl ether / 1) overnight, 2) reflux, 2 h
3: 1) sodium / 1) benzene, DMF, 2) benzene, reflux, 16 h
4: 60 percent / 10percent sodium hydroxide / methanol / 24 h
5: 90 percent / hexamethylphosphoric acid triamide / 3 h / 180 °C
View Scheme
参考文献
Vig, O. P.; Sharma, M. L.; Bhanot, R. K.; Malik, Neera
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. <B> 20, # 11 p. 970 - 971
反应条件
1: NaBH4 / ethanol
2: (i) Ac2O, Py, (ii) (pyrolysis)
View Scheme
参考文献
Winter,M. et al.
Helvetica Chimica Acta, 1979 , vol. 62, p. 135 - 139
反应条件
n-butyllithium in tetrahydrofuran; hexane
参考文献
Winter,M. et al.
Helvetica Chimica Acta, 1979 , vol. 62, p. 135 - 139
反应条件
1: 90 percent / PBr3, pyridine / diethyl ether / 1) overnight, 2) reflux, 2 h
2: 1) sodium / 1) benzene, DMF, 2) benzene, reflux, 16 h
3: 60 percent / 10percent sodium hydroxide / methanol / 24 h
4: 90 percent / hexamethylphosphoric acid triamide / 3 h / 180 °C
View Scheme
参考文献
Vig, O. P.; Sharma, M. L.; Bhanot, R. K.; Malik, Neera
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. <B> 20, # 11 p. 970 - 971
反应条件
1: 1) sodium / 1) benzene, DMF, 2) benzene, reflux, 16 h
2: 60 percent / 10percent sodium hydroxide / methanol / 24 h
3: 90 percent / hexamethylphosphoric acid triamide / 3 h / 180 °C
View Scheme
参考文献
Vig, O. P.; Sharma, M. L.; Bhanot, R. K.; Malik, Neera
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. <B> 20, # 11 p. 970 - 971
反应条件
1: 60 percent / 10percent sodium hydroxide / methanol / 24 h
2: 90 percent / hexamethylphosphoric acid triamide / 3 h / 180 °C
View Scheme
参考文献
Vig, O. P.; Sharma, M. L.; Bhanot, R. K.; Malik, Neera
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. <B> 20, # 11 p. 970 - 971
