4-(4,4-二甲基-4,5-二氢-1,3-恶唑-2-基)苯胺合成路线 (共 3 条)
反应条件
hydrogenchloride; thionyl chloride in ethylene glycol dimethyl ether
参考文献
American Cyanamid Company
Patent: US4136256 A1, 1979 ;
Title/Abstract Full Text Show Details
American Cyanamid Company
Patent: US4485105 A1, 1984 ;
反应条件
zinc(II) chloride
15 h; Irradiation;
参考文献
Clarke, David S.; Wood, Robin
Synthetic Communications, 1996 , vol. 26, # 7 p. 1335 - 1340
反应条件
palladium 10 on activated carbon; ammonium formate in ethanol
Reflux;
参考文献
Gordey, Erin E.; Yadav, Paras N.; Merrin, Marcus P.; Davies, Jill; Ward, Steven A.; Woodman, Grant M.J.; Sadowy, Amber L.; Smith, Todd G.; Gossage, Robert A.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 15 p. 4512 - 4515