ammonia in ethanol; dichloromethane; ethyl acetate

4-(N,N-dimethlyamino)pyridine; ammonia; triethylamine in diethyl ether a) RT, 2 h, b) reflux, 2 h;

1: thionyl chloride / 1,2-dimethoxy-ethane; CH2Cl2 / Heating 2: 78 percent / NH3, triethylamine, 4-(dimethylamino)pyridine / diethyl ether / a) RT, 2 h, b) reflux, 2 h View Scheme