2-羟基-4-甲基苯甲醛合成路线 （共 38 条）
反应条件
1: With tributyl-amine; tin(IV) chloride in toluene T=20°C; 0.5 h; 2: With formaldehyd in toluene T=100°C; 16 h;
参考文献
Faeh, Christoph; Kuehne, Holger; Luebbers, Thomas; Mattei, Patrizio; Maugeais, Cyrille; Pflieger, Philippe
Patent: US2007/185113 A1, 2007 ;
Location in patent: Page/Page column 12 ;
反应条件
triethylamine; magnesium chloride in tetrahydrofuran Inert atmosphereReflux;
参考文献
Phan, Diem H. T.; Kim, Byoungmoo; Dong, Vy M.
Journal of the American Chemical Society, 2009 , vol. 131, # 43 p. 15608 - 15609
反应条件
tin(IV) chloride; paraformaldehyde in ethyl acetate; toluene; pentane
参考文献
Challenger, Stephen; Cook, Andrew Simon; Gillmore, Adam Thomas; Middleton, Donald Stuart; Pryde, David Cameron; Stobie, Alan
Patent: US2003/105132 A1, 2003 ;
US 20030105132 A1
反应条件
(C4H9)3N; tin(IV) chloride in toluene T=100°C;
参考文献
Journal of Chemical Research, , # 6 p. 402 - 405
反应条件
AlCl3, aluminium chloride in dichloromethane T=20°C; 10 h; Inert atmosphere;
参考文献
Gensini, Martina; Altamura, Maria; Dimoulas, Tula; Fedi, Valentina; Giannotti, Danilo; Giuliani, Sandro; Guidi, Antonio; Harmat, Nicholas J. S.; Meini, Stefania; Nannicini, Rossano; Pasqui, Franco; Tramontana, Manuela; Triolo, Antonio; Maggi, Carlo Alberto
ChemMedChem, 2010 , vol. 5, # 1 p. 65 - 78
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; paraformaldehyde in tetrahydrofuran; diethyl ether; toluene
反应条件
boric acid in glycerol T=150 - 160°C; Duff Aldehyde Synthesis; 0.166667 h;
参考文献
Shen, Wei; Mao, Jianfeng; Sun, Juan; Sun, Minjie; Zhang, Can
Medicinal Chemistry Research, 2013 , vol. 22, # 4 p. 1630 - 1640
反应条件
zink cyanide; hydrogenchloride; benzene T=0°C; anschliessend Zufuegen von Aluminiumchlorid, weiteres 4-stuendiges Einleiten von Chlorwasserstoff, zum Schluss bei 50grad, und Zersetzen des Imidhydrochlorids mit siedender verduennter Salzsaeure;
参考文献
Journal of the Chemical Society, , p. 2226
参考文献
Chemische Berichte, , vol. 50, p. 395
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 20, # 4 p. 751 - 754
