6-氯-1,3-二甲基脲嘧啶合成路线 （共 66 条）
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in dichloromethane; water 2 h; Ambient temperature;
参考文献
Gogoi, Mukti; Sandhu, Jagir S.; Baruah, J. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 9 p. 851 - 852
反应条件
in ethanol T=60°C; 0.00833333 h; microwave irradiation;
参考文献
Fang, Woei-Ping; Cheng, Yuh-Tsyr; Cheng, Yann-Ru; Cherng, Yie-Jia
Tetrahedron, 2005 , vol. 61, # 12 p. 3107 - 3113
反应条件
bromine; acetic anhydride in acetic acid 0.5 h; Ambient temperature;
参考文献
Szilagyti; Wamhoff
Synthesis, 1981 , vol. No.9, p. 701 - 702
反应条件
palladium on activated charcoal; charcoal MgO; ethanol Hydrogenation;
参考文献
Pfleiderer; Schuendehuette
Justus Liebigs Annalen der Chemie, 1958 , vol. 612, p. 158,162
反应条件
1: 77 percent / 3 h / 170 °C 2: 35 percent / sodium nitrite / acetic acid / 0.67 h / 25 - 30 °C View Scheme
参考文献
Krasnov
Russian Journal of Organic Chemistry, 1998 , vol. 34, # 1 p. 115 - 119
反应条件
trifluoroacetic acid in benzene T=-25°C; 3 h; Irradiation;
参考文献
Heterocycles, , vol. 46, # 1 p. 141 - 144
反应条件
trifluoroacetic acid T=-25°C; 1 h; Irradiationvar. time, temp.; Product distributionMechanism;
参考文献
Heterocycles, , vol. 46, # 1 p. 141 - 144
反应条件
1: With water Alkaline conditions; 2: pH=7.5; Kinetics;
参考文献
Huang, Sha; Wong, Freeman M.; Gassner, George T.; Wu, Weiming
Tetrahedron Letters, 2011 , vol. 52, # 31 p. 3960 - 3962
反应条件
1: water 2: aqueous HCl; ethanol 3: Raney nickel; methanol / Hydrogenation 4: formic acid View Scheme
参考文献
Pfleiderer; Schuendehuette
Justus Liebigs Annalen der Chemie, 1958 , vol. 612, p. 158,162
参考文献
Kawahara, Norio; Itoh, Tsuneo; Ogura, Haruo; Watanabe, Kyoichi A.
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 63 - 66
