N,N'-二(苄氧羰基)-L-胱氨酸合成路线 （共 14 条）
反应条件
(i) Et3N, CHCl3, (ii) ClCO2Et, (iii) NH3; Multistep reaction;
参考文献
Baganz,H.; Dransch,G.
Chemische Berichte, 1960 , vol. 93, p. 784 - 791
反应条件
copper in N,N-dimethyl-formamide
T=120°C; 19 h;
参考文献
F. HOFFMANN-LA ROCHE AG
Patent: EP1236715 A2, 2002 ;
Location in patent: Example 6 ;
反应条件
1: With triphenylphosphine in tetrahydrofuran; water
T=20°C; 16 h; Inert atmosphere;
2: With sodium hydroxide in water
pH=10; Inert atmosphere;
3: With hydrogenchloride in water
pH=2; Inert atmosphere;
参考文献
Kramer, Jessica R.; Deming, Timothy J.
Journal of the American Chemical Society, 2012 , vol. 134, # 9 p. 4112 - 4115
反应条件
sulfuric acid; acetic acid; zinc in methanol; tetrachloromethane; ethyl acetate
参考文献
Bristol-Myers Squibb Company
Patent: US5508272 A1, 1996 ;
US 5508272 A
