2-甲酰基-4-硝基苯氧基乙酸合成路线 （共 13 条）
反应条件
1: aq. HCO2H
2: KOH / methanol
View Scheme
参考文献
Hullar,T.L.; Failla,D.L.
Journal of Medicinal Chemistry, 1969 , vol. 12, # 3 p. 420 - 424
反应条件
sodium hydroxide in water
3 h; Heating;
参考文献
Albanese, Domenico; Landini, Dario; Leone, Mario; Penso, Michele; Zenoni, Maurizio
Farmaco, 1998 , vol. 53, # 10-11 p. 709 - 717
反应条件
1: sodium hydroxide / water / 3 h / 30 - 100 °C
2: sulfuric acid; nitric acid / 5 - 35 °C
View Scheme
参考文献
CADILA HEALTHCARE LIMITED; DWIVEDI, Shriprakash Dhar; SINGH, Ramesh Chandra; CHAVDA, Rajendra Gokalbhai
Patent: WO2013/175499 A2, 2013 ;
